Clinical Trial - NCT03712605

Pembrolizumab Compared to Standard of Care Observation in Treating Patients With Completely Resected Stage I-III Merkel Cell Cancer, STAMP Study

Recruiting

Sponsor: National Cancer Institute (NCI)

Collaborators:

Information provided by (Responsible party): Sponsor

ClinicalTrials.gov Identifier: NCT03712605

Protocol Info

Short Description: Phase III MK-3475 vs SOC in Merkel Cell Carcinoma
Long Description: A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma
MGH Status: Open
Sponsor: Coop/ECOG
Disease Program: Melanoma

Next Steps


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Purpose

This phase III trial studies how well pembrolizumab works compared to standard of care observation in treating patients with stage I-III Merkel cell cancer that has been completely removed by surgery (resected). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Condition Title Intervention Phase
Pathologic Stage I Merkel Cell Carcinoma AJCC v8 Pathologic Stage II Merkel Cell Carcinoma AJCC v8 Pathologic Stage IIA Merkel Cell Carcinoma AJCC v8 Pathologic Stage IIB Merkel Cell Carcinoma AJCC v8 Pathologic Stage III Merkel Cell Carcinoma AJCC v8 Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8 Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8 Best Practice Pembrolizumab Radiation Therapy Phase 3
Study Type Interventional
Official Title STAMP: Surgically Treated Adjuvant Merkel Cell Carcinoma With Pembrolizumab, a Phase III Trial

Primary Outcome Measures

Recurrence free survival (RFS) [Time Frame: From randomization until disease recurrence or death from any cause; assessed up to 4.5 years] [Designated as safety issue: ]

OS [Time Frame: From randomization until death, assessed up to 4.5 years] [Designated as safety issue: ]


Secondary Outcome Measures

Impact of radiation therapy on RFS [Time Frame: Up to 4.5 years] [Designated as safety issue: ]

Impact of radiation therapy on OS [Time Frame: Up to 4.5 years] [Designated as safety issue: ]

Impact of radiation therapy on distant metastasis free survival (DMFS) [Time Frame: From randomization to distant metastasis, assessed up to 4.5 years] [Designated as safety issue: ]

Incidence of adverse events [Time Frame: Up to 4.5 years] [Designated as safety issue: ]

Estimated Enrollment: 280
Study Start Date: October 2018
Estimated Study Completion Date: October 2023
Estimated Primary Completion Date: October 2023
Arms Assigned Interventions

Experimental:Arm A (pembrolizumab, radiation therapy)

Patients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 21 days for up to 17 cycles in the absence of disease progression or unacceptable toxicity. Patients may also undergo standard of care radiation therapy within 14 days of day 1, cycle 1.
Radiation:Radiation Therapy
Undergo radiation therapy

Active Comparator:Arm B (standard of care observation, radiation therapy)

Patients receive standard of care observation every 3 months for 1 year, and then every 6 months for 5 years. Patients may also undergo standard of care radiation therapy within 14 days of day 1, cycle 1.
Other:Best Practice
Receive standard of care observation

Eligibility

Ages Eligible for Study: N/A-N/A

Genders Eligible for Study: All

Accepts Healthly Volunteers: No

Inclusion Criteria:

  • Patient must be >= 18 years of age
  • Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status: 0, 1, or 2 (However, those patients with a performance state of 3 because they are wheel chair bound due to congenital or traumatic events more than one year before the diagnosis of Merkel cell carcinoma are eligible).
  • Patient must not be pregnant or breast-feeding due to the unknown effects of the study drug in this setting. All patients of childbearing potential must have a blood test or urine study within 2 weeks prior to randomization to rule out pregnancy. A patient of childbearing potential is anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months).
  • Patients of childbearing potential, and sexually active males, on Arm A MK-3475 (pembrolizumab must not conceive or father children by using accepted and effective method(s) of contraception or by abstaining from sexual intercourse from the time of registration, while on study treatment, and continue for 120 days after the last dose of study treatment. For patients on Arm B only receiving radiation therapy, contraception use should be per institutional standard.
  • Patient must have a histological confirmation of diagnosis of Merkel cell carcinoma (MCC), pathologic stages (American Joint Committee on Cancer [AJCC] version 8) I-IIIb.
  • Stage I patients with negative sentinel lymph node biopsy are ineligible. Patients who have a positive biopsy or for whom no biopsy was done are eligible.
  • Patients with distant metastatic disease (stage IV) are ineligible.
  • The primary tumor must have grossly negative margins. (Microscopically positive margins are allowed).
  • Cancers of unknown primary that have regional disease only are eligible.
  • Complete nodal dissection is not required for eligibility.
  • Patients with all macroscopic Merkel cell carcinoma (either identified by physical exam or imaging) have been completely resected by surgery within 16 weeks before randomization.
  • All patients must have disease-free status documented by a complete physical examination and conventional imaging studies within 8 weeks prior to randomization.
  • Patient may not have a history of distant metastatic disease.
  • NOTE: Loco-regional recurrent disease is acceptable, as long as this is not metastatic (prior surgery with or without radiation therapy is acceptable).
  • For patients with initial presentation of Merkel cell carcinoma, patient must have no previous systemic therapy or radiation therapy prior to surgery for Merkel cell carcinoma and cannot have completed adjuvant radiation therapy for Merkel cell carcinoma more than 6 weeks prior to randomization. Patients actively undergoing radiation therapy or having completed adjuvant radiation therapy within 6 weeks of randomization are eligible, as long as resection date is within 16 weeks of randomization. Patients with prior radiation at a non-Radiation Oncology Core (IROC) provider are eligible for the trial. If the patient has not received radiation, and treatment at a Radiation Oncology Core (IROC) provider is not possible, the patient can start and complete radiation prior to randomization, with recommendations to follow radiation protocol guidelines with submission of treatment records.
  • White blood count >= 2000/uL (within 4 weeks prior to randomization).
  • Absolute neutrophil count (ANC) >= 1000/uL (within 4 weeks prior to randomization).
  • Platelets >= 75 x 10^3/uL (within 4 weeks prior to randomization).
  • Hemoglobin >= 8 g/dL (>= 80 g/L; may be transfused) (within 4 weeks prior to randomization).
  • Creatinine =< 2.0 x institutional upper limit of normal (ULN) (within 4 weeks prior to randomization).
  • Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x institutional ULN (within 4 weeks prior to randomization).
  • Total bilirubin =< 2.0 x institutional ULN, (except patients with Gilbert's syndrome, who must have a total bilirubin less than 3.0 mg/dL) (within 4 weeks prior to randomization).
  • Patients who are human immunodeficiency virus (HIV)+ with undetectable HIV viral load are eligible provided they meet all other protocol criteria for participation.
  • Patients with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection are eligible provided viral loads are undetectable. Patients on suppressive therapy are eligible.
  • Patients must not be on active immunosuppression, have a history of life threatening virus, have had other (beside non-melanoma skin cancers, or recent indolent cancers e.g.: resected low grade prostate cancer) invasive cancer diagnoses in the last two years, or have had immunotherapy of any kind within the last 2 years prior to randomization.
  • Patients must not have a history of (non-infectious) pneumonitis that required steroids or has current pneumonitis.
  • Operative notes from patient's surgical resection must be accessible.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT03712605

Locations

  • United States, Alabama
    • University of Alabama at Birmingham Cancer Center Birmingham, Alabama, United States, 35233
  • United States, Alaska
    • Anchorage Associates in Radiation Medicine Anchorage, Alaska, United States, 98508
    • Anchorage Radiation Therapy Center Anchorage, Alaska, United States, 99504
    • Alaska Breast Care and Surgery LLC Anchorage, Alaska, United States, 99508
    • Alaska Oncology and Hematology LLC Anchorage, Alaska, United States, 99508
    • Alaska Women's Cancer Care Anchorage, Alaska, United States, 99508
    • Anchorage Oncology Centre Anchorage, Alaska, United States, 99508
    • Katmai Oncology Group Anchorage, Alaska, United States, 99508
    • Providence Alaska Medical Center Anchorage, Alaska, United States, 99508
    • Fairbanks Memorial Hospital Fairbanks, Alaska, United States, 99701
  • United States, Arizona
    • Kingman Regional Medical Center Kingman, Arizona, United States, 86401
    • Mayo Clinic Hospital in Arizona Phoenix, Arizona, United States, 85054
    • Mayo Clinic in Arizona Scottsdale, Arizona, United States, 85259
    • Banner University Medical Center - Tucson Tucson, Arizona, United States, 85719
    • University of Arizona Cancer Center-North Campus Tucson, Arizona, United States, 85719
  • United States, Arkansas
    • Mercy Hospital Fort Smith Fort Smith, Arkansas, United States, 72903
  • United States, California
    • PCR Oncology Arroyo Grande, California, United States, 93420
    • Sutter Auburn Faith Hospital Auburn, California, United States, 95602
    • Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn, California, United States, 95603
    • Alta Bates Summit Medical Center-Herrick Campus Berkeley, California, United States, 94704
    • Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California, United States, 91505
    • Mills-Peninsula Medical Center Burlingame, California, United States, 94010
    • Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park, California, United States, 95682
    • Eden Hospital Medical Center Castro Valley, California, United States, 94546
    • Sutter Davis Hospital Davis, California, United States, 95616
    • Palo Alto Medical Foundation-Fremont Fremont, California, United States, 94538
    • Keck Medicine of USC Huntington Beach Huntington Beach, California, United States, 92648
    • UC San Diego Moores Cancer Center La Jolla, California, United States, 92093
    • Los Angeles County-USC Medical Center Los Angeles, California, United States, 90033
    • USC / Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033
    • Memorial Medical Center Modesto, California, United States, 95355
    • Palo Alto Medical Foundation-Camino Division Mountain View, California, United States, 94040
    • Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California, United States, 94040
    • USC Norris Oncology/Hematology-Newport Beach Newport Beach, California, United States, 92663
    • Sutter Cancer Research Consortium Novato, California, United States, 94945
    • UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California, United States, 92868
    • Palo Alto Medical Foundation Health Care Palo Alto, California, United States, 94301
    • Stanford Cancer Institute Palo Alto Palo Alto, California, United States, 94304
    • VA Palo Alto Health Care System Palo Alto, California, United States, 94304
    • Keck Medical Center of USC Pasadena Pasadena, California, United States, 91105
    • Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville, California, United States, 95661
    • Sutter Roseville Medical Center Roseville, California, United States, 95661
    • Sutter Medical Center Sacramento Sacramento, California, United States, 95816
    • California Pacific Medical Center-Pacific Campus San Francisco, California, United States, 94115
    • Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California, United States, 95065
    • Sutter Pacific Medical Foundation Santa Rosa, California, United States, 95403
    • Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California, United States, 94086
    • Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville, California, United States, 95687
    • Sutter Solano Medical Center/Cancer Center Vallejo, California, United States, 94589
  • United States, Colorado
    • Rocky Mountain Cancer Centers-Aurora Aurora, Colorado, United States, 80012
    • The Medical Center of Aurora Aurora, Colorado, United States, 80012
    • Boulder Community Foothills Hospital Boulder, Colorado, United States, 80303
    • Rocky Mountain Cancer Centers-Boulder Boulder, Colorado, United States, 80304
    • Rocky Mountain Cancer Centers - Centennial Centennial, Colorado, United States, 80112
    • Cancer Center of Colorado at Sloan's Lake Denver, Colorado, United States, 80204
    • National Jewish Health-Main Campus Denver, Colorado, United States, 80206
    • The Women's Imaging Center Denver, Colorado, United States, 80209
    • Colorado Blood Cancer Institute Denver, Colorado, United States, 80218
    • Presbyterian - Saint Lukes Medical Center - Health One Denver, Colorado, United States, 80218
    • Rocky Mountain Cancer Centers-Midtown Denver, Colorado, United States, 80218
    • SCL Health Saint Joseph Hospital Denver, Colorado, United States, 80218
    • Rocky Mountain Cancer Centers-Rose Denver, Colorado, United States, 80220
    • Rose Medical Center Denver, Colorado, United States, 80220
    • Western Surgical Care Denver, Colorado, United States, 80220
    • Mountain Blue Cancer Care Center - Swedish Englewood, Colorado, United States, 80113
    • Rocky Mountain Cancer Centers - Swedish Englewood, Colorado, United States, 80113
    • Swedish Medical Center Englewood, Colorado, United States, 80113
    • The Melanoma and Skin Cancer Institute Englewood, Colorado, United States, 80113
    • National Jewish Health-Western Hematology Oncology Golden, Colorado, United States, 80401
    • Saint Mary's Hospital and Regional Medical Center Grand Junction, Colorado, United States, 81501
    • North Colorado Medical Center Greeley, Colorado, United States, 80631
    • Good Samaritan Medical Center Lafayette, Colorado, United States, 80026
    • Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado, United States, 80228
    • Rocky Mountain Cancer Centers-Littleton Littleton, Colorado, United States, 80120
    • Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado, United States, 80124
    • Sky Ridge Medical Center Lone Tree, Colorado, United States, 80124
    • McKee Medical Center Loveland, Colorado, United States, 80539
    • National Jewish Health-Northern Hematology Oncology Thornton, Colorado, United States, 80260
    • Rocky Mountain Cancer Centers-Thornton Thornton, Colorado, United States, 80260
    • SCL Health Lutheran Medical Center Wheat Ridge, Colorado, United States, 80033
  • United States, Connecticut
    • Smilow Cancer Center/Yale-New Haven Hospital New Haven, Connecticut, United States, 06510
    • Yale University New Haven, Connecticut, United States, 06520
  • United States, District of Columbia
    • MedStar Georgetown University Hospital Washington, District of Columbia, United States, 20007
    • Sibley Memorial Hospital Washington, District of Columbia, United States, 20016
  • United States, Florida
    • UM Sylvester Comprehensive Cancer Center at Aventura Aventura, Florida, United States, 33180
    • UM Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida, United States, 33146
    • UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach, Florida, United States, 33442
    • Holy Cross Hospital Fort Lauderdale, Florida, United States, 33308
    • Regional Cancer Center-Lee Memorial Health System Fort Myers, Florida, United States, 33905
    • University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida, United States, 33136
    • Miami Cancer Institute Miami, Florida, United States, 33176
    • Orlando Health Cancer Institute Orlando, Florida, United States, 32806
    • UM Sylvester Comprehensive Cancer Center at Plantation Plantation, Florida, United States, 33324
    • Moffitt Cancer Center-International Plaza Tampa, Florida, United States, 33607
    • Moffitt Cancer Center - McKinley Campus Tampa, Florida, United States, 33612
    • Moffitt Cancer Center Tampa, Florida, United States, 33612
  • United States, Georgia
    • Emory University Hospital/Winship Cancer Institute Atlanta, Georgia, United States, 30322
    • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia, United States, 31405
    • Summit Cancer Care-Candler Savannah, Georgia, United States, 31405
  • United States, Idaho
    • Saint Alphonsus Cancer Care Center-Boise Boise, Idaho, United States, 83706
    • Saint Luke's Cancer Institute - Boise Boise, Idaho, United States, 83712
    • Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho, United States, 83605
    • Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho, United States, 83814
    • Walter Knox Memorial Hospital Emmett, Idaho, United States, 83617
    • Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho, United States, 83619
    • Idaho Urologic Institute-Meridian Meridian, Idaho, United States, 83642
    • Saint Luke's Cancer Institute - Meridian Meridian, Idaho, United States, 83642
    • Saint Alphonsus Medical Center-Nampa Nampa, Idaho, United States, 83686
    • Saint Luke's Cancer Institute - Nampa Nampa, Idaho, United States, 83686
    • Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho, United States, 83854
    • Kootenai Cancer Clinic Sandpoint, Idaho, United States, 83864
    • Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho, United States, 83301
  • United States, Illinois
    • Saint Anthony's Health Alton, Illinois, United States, 62002
    • Rush - Copley Medical Center Aurora, Illinois, United States, 60504
    • Illinois CancerCare-Bloomington Bloomington, Illinois, United States, 61704
    • Illinois CancerCare-Canton Canton, Illinois, United States, 61520
    • Memorial Hospital of Carbondale Carbondale, Illinois, United States, 62902
    • SIH Cancer Institute Carterville, Illinois, United States, 62918
    • Illinois CancerCare-Carthage Carthage, Illinois, United States, 62321
    • Centralia Oncology Clinic Centralia, Illinois, United States, 62801
    • Northwestern University Chicago, Illinois, United States, 60611
    • Rush University Medical Center Chicago, Illinois, United States, 60612
    • Carle on Vermilion Danville, Illinois, United States, 61832
    • Cancer Care Specialists of Illinois - Decatur Decatur, Illinois, United States, 62526
    • Decatur Memorial Hospital Decatur, Illinois, United States, 62526
    • Illinois CancerCare-Dixon Dixon, Illinois, United States, 61021
    • Carle Physician Group-Effingham Effingham, Illinois, United States, 62401
    • Crossroads Cancer Center Effingham, Illinois, United States, 62401
    • Illinois CancerCare-Eureka Eureka, Illinois, United States, 61530
    • Illinois CancerCare-Galesburg Galesburg, Illinois, United States, 61401
    • Western Illinois Cancer Treatment Center Galesburg, Illinois, United States, 61401
    • Illinois CancerCare-Kewanee Clinic Kewanee, Illinois, United States, 61443
    • Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois, United States, 60045
    • Illinois CancerCare-Macomb Macomb, Illinois, United States, 61455
    • Carle Physician Group-Mattoon/Charleston Mattoon, Illinois, United States, 61938
    • Good Samaritan Regional Health Center Mount Vernon, Illinois, United States, 62864
    • Cancer Care Center of O'Fallon O'Fallon, Illinois, United States, 62269
    • Illinois CancerCare-Ottawa Clinic Ottawa, Illinois, United States, 61350
    • Illinois CancerCare-Pekin Pekin, Illinois, United States, 61554
    • OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin, Illinois, United States, 61554
    • Illinois CancerCare-Peoria Peoria, Illinois, United States, 61615
    • OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria, Illinois, United States, 61615
    • Methodist Medical Center of Illinois Peoria, Illinois, United States, 61636
    • OSF Saint Francis Medical Center Peoria, Illinois, United States, 61637
    • Illinois CancerCare-Peru Peru, Illinois, United States, 61354
    • Valley Radiation Oncology Peru, Illinois, United States, 61354
    • Illinois CancerCare-Princeton Princeton, Illinois, United States, 61356
    • Southern Illinois University School of Medicine Springfield, Illinois, United States, 62702
    • Springfield Clinic Springfield, Illinois, United States, 62702
    • Memorial Medical Center Springfield, Illinois, United States, 62781
    • Southwest Illinois Health Services LLP Swansea, Illinois, United States, 62226
    • Carle Cancer Center Urbana, Illinois, United States, 61801
    • The Carle Foundation Hospital Urbana, Illinois, United States, 61801
    • Illinois CancerCare - Washington Washington, Illinois, United States, 61571
    • Rush-Copley Healthcare Center Yorkville, Illinois, United States, 60560
  • United States, Indiana
    • Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana, United States, 46202
    • Memorial Hospital of South Bend South Bend, Indiana, United States, 46601
  • United States, Iowa
    • Saint Anthony Regional Hospital Carroll, Iowa, United States, 51401
    • Mercy Hospital Cedar Rapids, Iowa, United States, 52403
    • Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa, United States, 52403
    • Jennie Edmundson Memorial Hospital Council Bluffs, Iowa, United States, 51502
    • Heartland Oncology and Hematology LLP Council Bluffs, Iowa, United States, 51503
    • Iowa Methodist Medical Center Des Moines, Iowa, United States, 50309
    • Medical Oncology and Hematology Associates-Des Moines Des Moines, Iowa, United States, 50309
    • Broadlawns Medical Center Des Moines, Iowa, United States, 50314
    • Iowa Lutheran Hospital Des Moines, Iowa, United States, 50316
    • Trinity Regional Medical Center Fort Dodge, Iowa, United States, 50501
    • Methodist West Hospital West Des Moines, Iowa, United States, 50266-7700
  • United States, Kansas
    • Coffeyville Regional Medical Center Coffeyville, Kansas, United States, 67337
    • Central Care Cancer Center - Garden City Garden City, Kansas, United States, 67846
    • Central Care Cancer Center - Great Bend Great Bend, Kansas, United States, 67530
    • HaysMed University of Kansas Health System Hays, Kansas, United States, 67601
    • University of Kansas Cancer Center Kansas City, Kansas, United States, 66160
    • Lawrence Memorial Hospital Lawrence, Kansas, United States, 66044
    • Olathe Health Cancer Center Olathe, Kansas, United States, 66061
    • University of Kansas Cancer Center-Overland Park Overland Park, Kansas, United States, 66210
    • Ascension Via Christi - Pittsburg Pittsburg, Kansas, United States, 66762
    • Salina Regional Health Center Salina, Kansas, United States, 67401
    • University of Kansas Health System Saint Francis Campus Topeka, Kansas, United States, 66606
    • University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas, United States, 66205
  • United States, Maine
    • Lafayette Family Cancer Center-EMMC Brewer, Maine, United States, 04412
  • United States, Maryland
    • Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States, 21287
  • United States, Massachusetts
    • Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114
    • Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02215
    • Mercy Medical Center Springfield, Massachusetts, United States, 01104
    • Baystate Medical Center Springfield, Massachusetts, United States, 01199
  • United States, Michigan
    • Saint Joseph Mercy Hospital Ann Arbor, Michigan, United States, 48106
    • Bronson Battle Creek Battle Creek, Michigan, United States, 49017
    • IHA Hematology Oncology Consultants-Brighton Brighton, Michigan, United States, 48114
    • Saint Joseph Mercy Brighton Brighton, Michigan, United States, 48114
    • IHA Hematology Oncology Consultants-Canton Canton, Michigan, United States, 48188
    • Saint Joseph Mercy Canton Canton, Michigan, United States, 48188
    • Caro Cancer Center Caro, Michigan, United States, 48723
    • IHA Hematology Oncology Consultants-Chelsea Chelsea, Michigan, United States, 48118
    • Saint Joseph Mercy Chelsea Chelsea, Michigan, United States, 48118
    • Hematology Oncology Consultants-Clarkston Clarkston, Michigan, United States, 48346
    • Newland Medical Associates-Clarkston Clarkston, Michigan, United States, 48346
    • Ascension Saint John Hospital Detroit, Michigan, United States, 48236
    • Great Lakes Cancer Management Specialists-Doctors Park East China Township, Michigan, United States, 48054
    • Genesee Cancer and Blood Disease Treatment Center Flint, Michigan, United States, 48503
    • Genesee Hematology Oncology PC Flint, Michigan, United States, 48503
    • Genesys Hurley Cancer Institute Flint, Michigan, United States, 48503
    • Hurley Medical Center Flint, Michigan, United States, 48503
    • Helen DeVos Children's Hospital at Spectrum Health Grand Rapids, Michigan, United States, 49503
    • Mercy Health Saint Mary's Grand Rapids, Michigan, United States, 49503
    • Spectrum Health at Butterworth Campus Grand Rapids, Michigan, United States, 49503
    • Academic Hematology Oncology Specialists Grosse Pointe Woods, Michigan, United States, 48236
    • Great Lakes Cancer Management Specialists-Van Elslander Cancer Center Grosse Pointe Woods, Michigan, United States, 48236
    • Michigan Breast Specialists-Grosse Pointe Woods Grosse Pointe Woods, Michigan, United States, 48236
    • Bronson Methodist Hospital Kalamazoo, Michigan, United States, 49007
    • West Michigan Cancer Center Kalamazoo, Michigan, United States, 49007
    • Ascension Borgess Cancer Center Kalamazoo, Michigan, United States, 49009
    • Borgess Medical Center Kalamazoo, Michigan, United States, 49048
    • Sparrow Hospital Lansing, Michigan, United States, 48912
    • Hope Cancer Clinic Livonia, Michigan, United States, 48154
    • Saint Mary Mercy Hospital Livonia, Michigan, United States, 48154
    • Great Lakes Cancer Management Specialists-Macomb Medical Campus Macomb, Michigan, United States, 48044
    • Michigan Breast Specialists-Macomb Township Macomb, Michigan, United States, 48044
    • Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan, United States, 48453
    • Mercy Health Mercy Campus Muskegon, Michigan, United States, 49444
    • Lakeland Hospital Niles Niles, Michigan, United States, 49120
    • Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan, United States, 49444
    • 21st Century Oncology-Pontiac Pontiac, Michigan, United States, 48341
    • Hope Cancer Center Pontiac, Michigan, United States, 48341
    • Newland Medical Associates-Pontiac Pontiac, Michigan, United States, 48341
    • Saint Joseph Mercy Oakland Pontiac, Michigan, United States, 48341
    • Huron Medical Center PC Port Huron, Michigan, United States, 48060
    • Lake Huron Medical Center Port Huron, Michigan, United States, 48060
    • Spectrum Health Reed City Hospital Reed City, Michigan, United States, 49677
    • Great Lakes Cancer Management Specialists-Rochester Hills Rochester Hills, Michigan, United States, 48309
    • Ascension Saint Mary's Hospital Saginaw, Michigan, United States, 48601
    • Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan, United States, 48604
    • Lakeland Medical Center Saint Joseph Saint Joseph, Michigan, United States, 49085
    • Marie Yeager Cancer Center Saint Joseph, Michigan, United States, 49085
    • Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan, United States, 48312
    • Ascension Saint Joseph Hospital Tawas City, Michigan, United States, 48764
    • Munson Medical Center Traverse City, Michigan, United States, 49684
    • Advanced Breast Care Center PLLC Warren, Michigan, United States, 48088
    • Great Lakes Cancer Management Specialists-Macomb Professional Building Warren, Michigan, United States, 48093
    • Macomb Hematology Oncology PC Warren, Michigan, United States, 48093
    • Michigan Breast Specialists-Warren Warren, Michigan, United States, 48093
    • Saint John Macomb-Oakland Hospital Warren, Michigan, United States, 48093
    • Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan, United States, 48661
    • Metro Health Hospital Wyoming, Michigan, United States, 49519
    • Huron Gastroenterology PC Ypsilanti, Michigan, United States, 48106
    • IHA Hematology Oncology Consultants-Ann Arbor Ypsilanti, Michigan, United States, 48197
  • United States, Minnesota
    • Riverwood Healthcare Center Aitkin, Minnesota, United States, 56431
    • Sanford Joe Lueken Cancer Center Bemidji, Minnesota, United States, 56601
    • Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota, United States, 56401
    • Fairview Ridges Hospital Burnsville, Minnesota, United States, 55337
    • Minnesota Oncology - Burnsville Burnsville, Minnesota, United States, 55337
    • Cambridge Medical Center Cambridge, Minnesota, United States, 55008
    • Mercy Hospital Coon Rapids, Minnesota, United States, 55433
    • Essentia Health - Deer River Clinic Deer River, Minnesota, United States, 56636
    • Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota, United States, 56501
    • Essentia Health Cancer Center Duluth, Minnesota, United States, 55805
    • Essentia Health Saint Mary's Medical Center Duluth, Minnesota, United States, 55805
    • Miller-Dwan Hospital Duluth, Minnesota, United States, 55805
    • Saint Luke's Hospital of Duluth Duluth, Minnesota, United States, 55805
    • Fairview Southdale Hospital Edina, Minnesota, United States, 55435
    • Lake Region Healthcare Corporation-Cancer Care Fergus Falls, Minnesota, United States, 56537
    • Essentia Health - Fosston Fosston, Minnesota, United States, 56542
    • Unity Hospital Fridley, Minnesota, United States, 55432
    • Essentia Health Hibbing Clinic Hibbing, Minnesota, United States, 55746
    • Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota, United States, 55369
    • Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota, United States, 55109
    • Saint John's Hospital - Healtheast Maplewood, Minnesota, United States, 55109
    • Abbott-Northwestern Hospital Minneapolis, Minnesota, United States, 55407
    • Hennepin County Medical Center Minneapolis, Minnesota, United States, 55415
    • Health Partners Inc Minneapolis, Minnesota, United States, 55454
    • Monticello Cancer Center Monticello, Minnesota, United States, 55362
    • New Ulm Medical Center New Ulm, Minnesota, United States, 56073
    • Essentia Health - Park Rapids Park Rapids, Minnesota, United States, 56470
    • Fairview Northland Medical Center Princeton, Minnesota, United States, 55371
    • North Memorial Medical Health Center Robbinsdale, Minnesota, United States, 55422
    • Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905
    • Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota, United States, 55416
    • Regions Hospital Saint Paul, Minnesota, United States, 55101
    • United Hospital Saint Paul, Minnesota, United States, 55102
    • Essentia Health Sandstone Sandstone, Minnesota, United States, 55072
    • Lakeview Hospital Stillwater, Minnesota, United States, 55082
    • Sanford Thief River Falls Medical Center Thief River Falls, Minnesota, United States, 56701
    • Essentia Health Virginia Clinic Virginia, Minnesota, United States, 55792
    • Ridgeview Medical Center Waconia, Minnesota, United States, 55387
    • Rice Memorial Hospital Willmar, Minnesota, United States, 56201
    • Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota, United States, 55125
    • Sanford Cancer Center Worthington Worthington, Minnesota, United States, 56187
    • Fairview Lakes Medical Center Wyoming, Minnesota, United States, 55092
  • United States, Missouri
    • Saint Louis Cancer and Breast Institute-Ballwin Ballwin, Missouri, United States, 63011
    • Central Care Cancer Center - Bolivar Bolivar, Missouri, United States, 65613
    • Parkland Health Center-Bonne Terre Bonne Terre, Missouri, United States, 63628
    • Cox Cancer Center Branson Branson, Missouri, United States, 65616
    • Saint Francis Medical Center Cape Girardeau, Missouri, United States, 63703
    • Southeast Cancer Center Cape Girardeau, Missouri, United States, 63703
    • Siteman Cancer Center at West County Hospital Creve Coeur, Missouri, United States, 63141
    • Parkland Health Center - Farmington Farmington, Missouri, United States, 63640
    • Capital Region Southwest Campus Jefferson City, Missouri, United States, 65109
    • Freeman Health System Joplin, Missouri, United States, 64804
    • Mercy Hospital Joplin Joplin, Missouri, United States, 64804
    • Truman Medical Centers Kansas City, Missouri, United States, 64108
    • University of Kansas Cancer Center - North Kansas City, Missouri, United States, 64154
    • University of Kansas Cancer Center at North Kansas City Hospital North Kansas City, Missouri, United States, 64116
    • Delbert Day Cancer Institute at PCRMC Rolla, Missouri, United States, 65401
    • Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri, United States, 65401
    • Heartland Regional Medical Center Saint Joseph, Missouri, United States, 64506
    • Saint Louis Cancer and Breast Institute-South City Saint Louis, Missouri, United States, 63109
    • Washington University School of Medicine Saint Louis, Missouri, United States, 63110
    • Mercy Hospital South Saint Louis, Missouri, United States, 63128
    • Siteman Cancer Center-South County Saint Louis, Missouri, United States, 63129
    • Missouri Baptist Medical Center Saint Louis, Missouri, United States, 63131
    • Siteman Cancer Center at Christian Hospital Saint Louis, Missouri, United States, 63136
    • Mercy Hospital Saint Louis Saint Louis, Missouri, United States, 63141
    • Siteman Cancer Center at Saint Peters Hospital Saint Peters, Missouri, United States, 63376
    • Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri, United States, 63670
    • Mercy Hospital Springfield Springfield, Missouri, United States, 65804
    • CoxHealth South Hospital Springfield, Missouri, United States, 65807
    • Missouri Baptist Sullivan Hospital Sullivan, Missouri, United States, 63080
    • Missouri Baptist Outpatient Center-Sunset Hills Sunset Hills, Missouri, United States, 63127
    • Mercy Hospital Washington Washington, Missouri, United States, 63090
  • United States, Montana
    • Community Hospital of Anaconda Anaconda, Montana, United States, 59711
    • Billings Clinic Cancer Center Billings, Montana, United States, 59101
    • Saint Vincent Healthcare Billings, Montana, United States, 59101
    • Saint Vincent Frontier Cancer Center Billings, Montana, United States, 59102
    • Bozeman Deaconess Hospital Bozeman, Montana, United States, 59715
    • Saint James Community Hospital and Cancer Treatment Center Butte, Montana, United States, 59701
    • Benefis Healthcare- Sletten Cancer Institute Great Falls, Montana, United States, 59405
    • Great Falls Clinic Great Falls, Montana, United States, 59405
    • Saint Peter's Community Hospital Helena, Montana, United States, 59601
    • Kalispell Regional Medical Center Kalispell, Montana, United States, 59901
    • Saint Patrick Hospital - Community Hospital Missoula, Montana, United States, 59802
    • Community Medical Hospital Missoula, Montana, United States, 59804
  • United States, Nebraska
    • Nebraska Methodist Hospital Omaha, Nebraska, United States, 68114
  • United States, Nevada
    • Carson Tahoe Regional Medical Center Carson City, Nevada, United States, 89703
    • Cancer and Blood Specialists-Henderson Henderson, Nevada, United States, 89052
    • Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada, United States, 89052
    • Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson, Nevada, United States, 89052
    • Las Vegas Cancer Center-Henderson Henderson, Nevada, United States, 89052
    • OptumCare Cancer Care at Seven Hills Henderson, Nevada, United States, 89052
    • 21st Century Oncology-Henderson Henderson, Nevada, United States, 89074
    • Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada, United States, 89074
    • Las Vegas Urology - Green Valley Henderson, Nevada, United States, 89074
    • Las Vegas Urology - Pebble Henderson, Nevada, United States, 89074
    • Urology Specialists of Nevada - Green Valley Henderson, Nevada, United States, 89074
    • Las Vegas Urology - Pecos Las Vegas, Nevada, United States, 89074
    • Desert West Surgery Las Vegas, Nevada, United States, 89102
    • OptumCare Cancer Care at Charleston Las Vegas, Nevada, United States, 89102
    • University Medical Center of Southern Nevada Las Vegas, Nevada, United States, 89102
    • Hope Cancer Care of Nevada Las Vegas, Nevada, United States, 89103
    • Cancer and Blood Specialists-Shadow Las Vegas, Nevada, United States, 89106
    • Radiation Oncology Centers of Nevada Central Las Vegas, Nevada, United States, 89106
    • Urology Specialists of Nevada - Central Las Vegas, Nevada, United States, 89106
    • 21st Century Oncology Las Vegas, Nevada, United States, 89109
    • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Las Vegas, Nevada, United States, 89109
    • Sunrise Hospital and Medical Center Las Vegas, Nevada, United States, 89109
    • HealthCare Partners Medical Group Oncology/Hematology-San Martin Las Vegas, Nevada, United States, 89113
    • Las Vegas Prostate Cancer Center Las Vegas, Nevada, United States, 89113
    • Las Vegas Urology - Sunset Las Vegas, Nevada, United States, 89113
    • Urology Specialists of Nevada - Southwest Las Vegas, Nevada, United States, 89113
    • Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada, United States, 89119
    • 21st Century Oncology-Vegas Tenaya Las Vegas, Nevada, United States, 89128
    • Ann M Wierman MD LTD Las Vegas, Nevada, United States, 89128
    • Cancer and Blood Specialists-Tenaya Las Vegas, Nevada, United States, 89128
    • Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada, United States, 89128
    • HealthCare Partners Medical Group Oncology/Hematology-Tenaya Las Vegas, Nevada, United States, 89128
    • Las Vegas Urology - Cathedral Rock Las Vegas, Nevada, United States, 89128
    • Las Vegas Urology - Smoke Ranch Las Vegas, Nevada, United States, 89128
    • OptumCare Cancer Care at MountainView Las Vegas, Nevada, United States, 89128
    • Urology Specialists of Nevada - Northwest Las Vegas, Nevada, United States, 89128
    • Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada, United States, 89135
    • Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada, United States, 89144
    • Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada, United States, 89144
    • Summerlin Hospital Medical Center Las Vegas, Nevada, United States, 89144
    • Las Vegas Cancer Center-Medical Center Las Vegas, Nevada, United States, 89148-2405
    • 21st Century Oncology-Fort Apache Las Vegas, Nevada, United States, 89148
    • Comprehensive Cancer Centers of Nevada Las Vegas, Nevada, United States, 89148
    • OptumCare Cancer Care at Fort Apache Las Vegas, Nevada, United States, 89148
    • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Las Vegas, Nevada, United States, 89149
    • Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada, United States, 89169
    • University Cancer Center Las Vegas, Nevada, United States, 89169
    • Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada, United States, 89048
    • Renown Regional Medical Center Reno, Nevada, United States, 89502
    • Saint Mary's Regional Medical Center Reno, Nevada, United States, 89503
    • Radiation Oncology Associates Reno, Nevada, United States, 89509
  • United States, New Jersey
    • Hackensack University Medical Center Hackensack, New Jersey, United States, 07601
    • Saint Barnabas Medical Center Livingston, New Jersey, United States, 07039
    • Morristown Medical Center Morristown, New Jersey, United States, 07960
    • Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08903
    • Overlook Hospital Summit, New Jersey, United States, 07902
  • United States, New York
    • Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York, United States, 10016
    • University of Rochester Rochester, New York, United States, 14642
    • Stony Brook University Medical Center Stony Brook, New York, United States, 11794
  • United States, North Carolina
    • Messino Cancer Centers Asheville, North Carolina, United States, 28806
    • Wake Forest University at Clemmons Clemmons, North Carolina, United States, 27012
    • Duke University Medical Center Durham, North Carolina, United States, 27710
    • East Carolina University Greenville, North Carolina, United States, 27834
    • Margaret R Pardee Memorial Hospital Hendersonville, North Carolina, United States, 28791
    • Wake Forest Baptist Health - Hematology Oncology - Statesville Statesville, North Carolina, United States, 28677
    • Wake Forest Baptist Health - Wilkes Medical Center Wilkesboro, North Carolina, United States, 28659
    • Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157
  • United States, North Dakota
    • Sanford Bismarck Medical Center Bismarck, North Dakota, United States, 58501
    • Essentia Health Cancer Center-South University Clinic Fargo, North Dakota, United States, 58103
    • Sanford South University Medical Center Fargo, North Dakota, United States, 58103
    • Sanford Medical Center Fargo Fargo, North Dakota, United States, 58104
    • Sanford Broadway Medical Center Fargo, North Dakota, United States, 58122
    • Sanford Roger Maris Cancer Center Fargo, North Dakota, United States, 58122
    • Essentia Health - Jamestown Clinic Jamestown, North Dakota, United States, 58401
  • United States, Ohio
    • UHHS-Chagrin Highlands Medical Center Beachwood, Ohio, United States, 44122
    • Geauga Hospital Chardon, Ohio, United States, 44024
    • University of Cincinnati Cancer Center-UC Medical Center Cincinnati, Ohio, United States, 45219
    • Case Western Reserve University Cleveland, Ohio, United States, 44106
    • MetroHealth Medical Center Cleveland, Ohio, United States, 44109
    • Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195
    • Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210
    • UH Seidman Cancer Center at Lake Health Mentor Campus Mentor, Ohio, United States, 44060
    • UH Seidman Cancer Center at Southwest General Hospital Middleburg Heights, Ohio, United States, 44130
    • University Hospitals Parma Medical Center Parma, Ohio, United States, 44129
    • University Hospitals Portage Medical Center Ravenna, Ohio, United States, 44266
    • North Coast Cancer Care Sandusky, Ohio, United States, 44870
    • UH Seidman Cancer Center at Firelands Regional Medical Center Sandusky, Ohio, United States, 44870
    • Cleveland Clinic Cancer Center Strongsville Strongsville, Ohio, United States, 44136
    • University Hospitals Sharon Health Center Wadsworth, Ohio, United States, 44281
    • University of Cincinnati Cancer Center-West Chester West Chester, Ohio, United States, 45069
    • UH Seidman Cancer Center at Saint John Medical Center Westlake, Ohio, United States, 44145
    • Cleveland Clinic Wooster Family Health and Surgery Center Wooster, Ohio, United States, 44691
  • United States, Oklahoma
    • Cancer Centers of Southwest Oklahoma Research Lawton, Oklahoma, United States, 73505
    • University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma, United States, 73104
    • Mercy Hospital Oklahoma City Oklahoma City, Oklahoma, United States, 73120
    • Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma, United States, 74146
  • United States, Oregon
    • Saint Alphonsus Medical Center-Baker City Baker City, Oregon, United States, 97814
    • Saint Charles Health System Bend, Oregon, United States, 97701
    • Clackamas Radiation Oncology Center Clackamas, Oregon, United States, 97015
    • Providence Cancer Institute Clackamas Clinic Clackamas, Oregon, United States, 97015
    • Bay Area Hospital Coos Bay, Oregon, United States, 97420
    • Providence Newberg Medical Center Newberg, Oregon, United States, 97132
    • Saint Alphonsus Medical Center-Ontario Ontario, Oregon, United States, 97914
    • Providence Portland Medical Center Portland, Oregon, United States, 97213
    • Providence Saint Vincent Medical Center Portland, Oregon, United States, 97225
    • Oregon Health and Science University Portland, Oregon, United States, 97239
    • Saint Charles Health System-Redmond Redmond, Oregon, United States, 97756
  • United States, Pennsylvania
    • Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania, United States, 18103
    • Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania, United States, 18017
    • Geisinger Medical Center Danville, Pennsylvania, United States, 17822
    • Pocono Medical Center East Stroudsburg, Pennsylvania, United States, 18301
    • Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania, United States, 18201
    • Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania, United States, 18201
    • Penn State Milton S Hershey Medical Center Hershey, Pennsylvania, United States, 17033-0850
    • Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania, United States, 17837
    • Lewistown Hospital Lewistown, Pennsylvania, United States, 17044
    • University of Pennsylvania/Abramson Cancer Center Philadelphia, Pennsylvania, United States, 19104
    • Thomas Jefferson University Hospital Philadelphia, Pennsylvania, United States, 19107
    • Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111
    • University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232
    • UPMC-Shadyside Hospital Pittsburgh, Pennsylvania, United States, 15232
    • Geisinger Cancer Services-Pottsville Pottsville, Pennsylvania, United States, 17901
    • Community Medical Center Scranton, Pennsylvania, United States, 18510
    • Geisinger Medical Oncology-Selinsgrove Selinsgrove, Pennsylvania, United States, 17870
    • Geisinger Medical Group State College, Pennsylvania, United States, 16801
    • Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania, United States, 18711
  • United States, South Carolina
    • Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina, United States, 29910
    • Medical University of South Carolina Charleston, South Carolina, United States, 29425
    • Gibbs Cancer Center-Gaffney Gaffney, South Carolina, United States, 29341
    • Gibbs Cancer Center-Pelham Greer, South Carolina, United States, 29651
    • South Carolina Cancer Specialists PC Hilton Head Island, South Carolina, United States, 29926-3827
    • North Grove Medical Park Spartanburg, South Carolina, United States, 29303
    • Spartanburg Medical Center Spartanburg, South Carolina, United States, 29303
    • Spartanburg Medical Center - Mary Black Campus Spartanburg, South Carolina, United States, 29307
    • MGC Hematology Oncology-Union Union, South Carolina, United States, 29379
  • United States, South Dakota
    • Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota, United States, 57104
    • Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota, United States, 57117-5134
  • United States, Tennessee
    • University of Tennessee - Knoxville Knoxville, Tennessee, United States, 37920
  • United States, Texas
    • UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas, United States, 75390
  • United States, Utah
    • Huntsman Cancer Institute/University of Utah Salt Lake City, Utah, United States, 84112
  • United States, Virginia
    • University of Virginia Cancer Center Charlottesville, Virginia, United States, 22908
    • Inova Schar Cancer Institute Fairfax, Virginia, United States, 22031
    • Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia, United States, 23298
  • United States, Washington
    • Providence Regional Cancer System-Aberdeen Aberdeen, Washington, United States, 98520
    • Overlake Medical Center Bellevue, Washington, United States, 98004
    • PeaceHealth Saint Joseph Medical Center Bellingham, Washington, United States, 98225
    • Providence Regional Cancer System-Centralia Centralia, Washington, United States, 98531
    • Swedish Cancer Institute-Edmonds Edmonds, Washington, United States, 98026
    • Providence Regional Cancer Partnership Everett, Washington, United States, 98201
    • Swedish Cancer Institute-Issaquah Issaquah, Washington, United States, 98029
    • Kadlec Clinic Hematology and Oncology Kennewick, Washington, United States, 99336
    • Providence Regional Cancer System-Lacey Lacey, Washington, United States, 98503
    • PeaceHealth Saint John Medical Center Longview, Washington, United States, 98632
    • Jefferson Healthcare Port Townsend, Washington, United States, 98368
    • Valley Medical Center Renton, Washington, United States, 98055
    • Pacific Gynecology Specialists Seattle, Washington, United States, 98104
    • Swedish Medical Center-Ballard Campus Seattle, Washington, United States, 98107
    • Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109
    • Seattle Cancer Care Alliance Seattle, Washington, United States, 98109
    • Swedish Medical Center-First Hill Seattle, Washington, United States, 98122-4307
    • Swedish Medical Center-Cherry Hill Seattle, Washington, United States, 98122-5711
    • University of Washington Medical Center - Montlake Seattle, Washington, United States, 98195
    • PeaceHealth United General Medical Center Sedro-Woolley, Washington, United States, 98284
    • Providence Regional Cancer System-Shelton Shelton, Washington, United States, 98584
    • PeaceHealth Southwest Medical Center Vancouver, Washington, United States, 98664
    • Providence Saint Mary Regional Cancer Center Walla Walla, Washington, United States, 99362
    • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington, United States, 98902
    • Providence Regional Cancer System-Yelm Yelm, Washington, United States, 98597
  • United States, Wisconsin
    • ThedaCare Regional Cancer Center Appleton, Wisconsin, United States, 54911
    • Duluth Clinic Ashland Ashland, Wisconsin, United States, 54806
    • Northwest Wisconsin Cancer Center Ashland, Wisconsin, United States, 54806
    • Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin, United States, 54701
    • Mayo Clinic Health System-Eau Claire Clinic Eau Claire, Wisconsin, United States, 54701
    • Bellin Memorial Hospital Green Bay, Wisconsin, United States, 54301
    • Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin, United States, 54301
    • Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin, United States, 54303
    • Marshfield Medical Center-Marshfield Marshfield, Wisconsin, United States, 54449
    • Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin, United States, 53051
    • Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226
    • Marshfield Clinic-Minocqua Center Minocqua, Wisconsin, United States, 54548
    • Cancer Center of Western Wisconsin New Richmond, Wisconsin, United States, 54017
    • Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin, United States, 54868
    • Marshfield Clinic Stevens Point Center Stevens Point, Wisconsin, United States, 54482
    • Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin, United States, 54235-1495
    • Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin, United States, 53095
    • Diagnostic and Treatment Center Weston, Wisconsin, United States, 54476
    • Marshfield Medical Center - Weston Weston, Wisconsin, United States, 54476
  • United States, Wyoming
    • Cheyenne Regional Medical Center-West Cheyenne, Wyoming, United States, 82001
    • Billings Clinic-Cody Cody, Wyoming, United States, 82414
    • Welch Cancer Center Sheridan, Wyoming, United States, 82801

Sponsors and Collaborators

National Cancer Institute (NCI)

More Information

No publications provided

Responsible Party: Sponsor
ClinicalTrials.gov Identifier: NCT03712605
Other Study ID Numbers: NCI-2018-02217
Study First Received:
Last Updated:
Health Authority:

Additional relevant MeSH terms:

Carcinoma, Merkel Cell

Carcinoma

Pembrolizumab

Next Steps


If you are interested in this protocol or in other treatment options at Massachusetts General Hospital, please Request a Consultation.







ClinicalTrials.gov processed this data on October 14, 2021