panitumumab
A human monoclonal antibody produced in transgenic mice that attaches to the transmembrane epidermal growth factor (EGF) receptor. Panitumumab may inhibit autocrine EGF stimulation of tumor cells that express the EGF receptor, thereby inhibiting tumor cell proliferation.
Drug Code Name
ABX-EGF
Drug Short Name
MOAB ABX-EGF
Synonyms
clone E7.6.3
monoclonal antibody ABX-EGF
US Brand Names
Vectibix