trastuzumab
A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas..
Drug Code Name
ABP 980
PF-05280014
RO0452317
Drug Short Name
MOAB HER2
rhuMAb HER22
Synonyms
anti-c-erB-2
anti-c-erbB2 monoclonal antibody
anti-ERB-2
anti-erbB-2
anti-erbB2 monoclonal antibody
anti-HER2/c-erbB2 monoclonal antibody
anti-p185-HER2
Herceptin biosimilar PF-05280014
Herceptin trastuzumab biosimilar PF-05280014
MOAB HER2
monoclonal antibody c-erb-2
monoclonal antibody HER2
trastuzumab biosimilar ABP 980
trastuzumab biosimilar HLX02
trastuzumab biosimilar PF-05280014
trastuzumab biosimilar SB3
US Brand Names
Herceptin
Ogivri