Arms |
Assigned Interventions |
Experimental:Pole Mutated Endometrial Cancer
Participants with Pole mutated endometrial cancer Avelumab will be administered intravenously twice per cycle
|
Experimental:MSS Endometrial Cancer
Participants with MSS mutated endometrial cancer Avelumab will be administered intravenously twice per cycle
|
Experimental:MSS Avelumab/Talazoparib Combination Arm
Participants with MSS mutated endometrial cancer Avelumab will be administered intravenously twice per cycle Talazoparib will be administered one time per day by mouth
|
Drug:Talazoparib Talazoparib will be taken one time per day by mouth Each Cycle lasts 28 days |
Experimental:MSS Avelumab/Axitinib Combination Arm
Participants with MSS mutated endometrial cancer Avelumab will be administered intravenously twice per cycle Axitinib will be administered twice per day by mouth
|
Drug:Axitinib Axitinib will be taken twice per day by mouth Each Cycle lasts 28 days |